Anti-Phospho-SHIP Rabbit Polyclonal Antibody

Supplier: STEMCELL Technologies
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STMC60142EA 472 GBP
STMC60142
Anti-Phospho-SHIP Rabbit Polyclonal Antibody
Antibodies
Rabbit polyclonal antibody against human, mouse phosphoSHIP, unconjugated.

  • Granulocytes
  • Subsets
  • Lymphocytes
  • Myeloid cells

Phospho-SHIP is a highly phosphorylated form of SHIP (also called SHIP1). SH2-containing inositol phosphatase (SHIP) is a 145 kDa hematopoietic-restricted protein that becomes tyrosine-phosphorylated and associated with the adaptor protein, Shc, following cytokine, growth factor, chemokine, and immunoreceptor stimulation. SHIP also hydrolyzes the critical phosphatidylinositol (PI)-3-kinase (PI3K)-generated second messenger, PI-3,4,5-P3 (PIP3), to PI-3,4-P2 1,2 and therefore acts as an important negative regulator of the PI3K pathway. This antibody reacts with mouse and human tyrosine-phosphorylated SHIP.

Type: Anti-Phospho-SHIP Rabbit Polyclonal Antibody
Antigen: Phospho-SHIP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse
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