Anti-CD71 Mouse Monoclonal Antibody [clone: OKT9] (PE)

Supplier: STEMCELL Technologies
Ratings: (No Reviews)

Total Ratings: 0
Avg. Ratings: 0.0 out of 5

STMC60106PE.1EA 158 GBP
STMC60106PE.1 STMC60106PE
Anti-CD71 Mouse Monoclonal Antibody [clone: OKT9] (PE)
Antibodies
Mouse monoclonal IgG1 antibody against human CD71 (transferrin receptor), PE-conjugated.

  • Erythroid cells

The OKT9 antibody reacts with CD71 (transferrin receptor), an ~180 - 190 kDa disulfide-bonded homodimer and type 2 transmembrane glycoprotein expressed at high levels on a broad range of actively proliferating cells, as well as reticulocytes, monocytes, macrophages and marrow stromal cells. Surface levels are low on resting leukocytes but are upregulated on lymphocytes, monocytes and macrophages following antigen or mitogen stimulation. Expression is lost during differentiation of reticulocytes into mature erythrocytes. CD71 mediates uptake of transferrin–iron complexes through receptor-mediated endocytosis and recycling of the apotransferrin–receptor complex to the cell surface. CD71 has been employed as a marker for evaluating erythroid precursors and for assessing disorders such as erythroid leukemia and myelodysplastic syndrome. It has also served as a target for drug delivery. The OKT9 antibody binds an epitope that reportedly overlaps with that of antibody clone CY1G4 but is distinct from the ligand binding site for transferrin.

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: CD71
Clonality: Monoclonal
Clone: OKT9
Conjugation: PE
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR