(S)-(+)-Camptothecin ≥98%
Supplier: ENZO LIFE SCIENCESTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
Potent antitumor agent
Potent antitumor agent. Inhibitor of DNA-topoisomerase I. Activates p53 resulting in upregulated expression of TRAIL-R2 (DR5) and Bak to overcome TRAIL resistance in Bax-deficient human colon carcinoma cells. Inhinbits Tat-mediated transactivation of HIV-1. Induces apoptosis in osteosarcoma and hepatoma cells. Suppresses nitric oxide (NO) biosynthesis.
Isolated from Mappia foetida Miers (Nothapodytes foetida (Wt.) Sleumer).
Formula:
C₂₀H₁₆N₂O₄ |
MDL Number:
MFCD00081076 CAS Number: 7689-03-4 |
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