SC-236 ≥95% (by HPLC)
Supplier: ENZO LIFE SCIENCES AGTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
Synonyms:
4-[5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulphonamide, 4-(5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulphonamide
Highly selective and potent inhibitor of cyclooxygenase-2 (IC50=10nM for COX-2 versus IC50=17.8µM for COX-1) with antitumor properties. Exhibits longer half-life time and reduced gastric toxicity in fasting rat model. Has antitumor properties and has been shown to induce apoptosis and bFGF and VEGF-driven angiogenesis. Potent antimetastatic activity against both spontaneous metastases arising following primary tumour excision and experimental metastases.
- COX inhibitor
White to off-white crystalline powder.
Soluble in DMSO.
Formula:
C₁₆H₁₁ClF₃N₃O₂S MW: 401.8 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00941297 CAS Number: 170569-86-5 |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...