Tyrphostin AG 1478 ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Ratings:
(No Reviews)
Total Ratings: 0
Avg. Ratings: 0.0 out of 5
ALX270036M001
ALX270036M005
ENZOALX270036M001EA
55.1
GBP
ENZOALX270036M001
ENZOALX270036M005
Tyrphostin AG 1478 ≥98% (by HPLC)
Tyrphostin AG 1478
EGFR inhibitor
Potent and selective inhibitor of EGFR (IC50 = 3nM). Reduces EGF-stimulated DNA synthesis in Rat-1 fibroblasts by ~75% at 0.25μM. Blocks EGF-dependent src-family kinase activation and p21/Cip 1/WAF1 induction in A431 cells. Also inhibits H2O2-induced stimulation of amphiregulin expression in rat gastric epithelium (RGM 1) cells.
Formula:
C₁₆H₁₄ClN₃O₂ |
MDL Number:
MFCD00270914 CAS Number: 153436-53-4 |
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