Sodium iodoacetate ≥99.5% (by total nitrogen and titration analysis), BioUltra, Sigma-Aldrich®

Supplier: Merck
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Synonyms: Sodium 2-iodoacetate, Iodoacetic Acid, Sodium Salt

57858-25G-F 57858-5G-F
SIAL57858-25G-FEA 878 GBP
SIAL57858-25G-F SIAL57858-5G-F
Sodium iodoacetate ≥99.5% (by total nitrogen and titration analysis), BioUltra, Sigma-Aldrich®
Sodium iodoacetate

Reagent for the modification of cysteine residues in proteins


  • Assay: ≥99.5%
  • Solubility: Methanol Soluble (0.1 M at 20 °C), clear and colorless
  • Melting Point: 208 °C (dec.)(lit.)


Used in protein sequencing (including by sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains and to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

Formula: C₂H₂INaO₂
MW: 207.93 g/mol
Melting Pt: 208…210 °C
Flash Pt: 208
Storage Temperature: Freezer
MDL Number: MFCD00002686
CAS Number: 305-53-3
EINECS: 206-165-7
UN: 2811
ADR: 6.1 III

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Specification Test Results

Insoluble matter passes filter test
Water ≤0.5%


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