Human Recombinant IL-4 (from E. coli)

Supplier: Shenandoah Biotechnology
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100-09AF-100UG 100-09AF-1MG 100-09AF-20UG 100-09AF-500UG 100-09AF-5UG
SHBT100-09AF-100UGEA 476 GBP
SHBT100-09AF-100UG SHBT100-09AF-1MG SHBT100-09AF-20UG SHBT100-09AF-500UG SHBT100-09AF-5UG
Human Recombinant IL-4 (from E. coli)
Proteins and Peptides

Interleukin 4 (IL-4) is an immunomodulatory cytokine that functions to induce naïve helper T cells to differentiate into type 2 T helper (Th2) cells. Th2 cells subsequently produce more IL-4 in a positive feedback loop. IL-4 also promotes immunoglobulin IgG to IgE isotype switching on B cells. IL-4 binds the IL-4Rα receptor to activate STAT6 signaling.


  • High quality
  • Low endotoxin
  • Affordable


Caution: This product is for research use only and is not for use in humans.

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SPECIFICATIONS

Protein/peptide name IL-4 (AF)
Environmentally Preferable
Protein synonyms BCGF|B-cell stimulatory factor-1|BCDF|BSF-1
Protein/peptide type Recombinant
Protein function Cytokine
Species Human
Source E. coli
Conjugation Unconjugated
Gene ID P05112
Sequence MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
Protease-free N
Animal-free Y
Nuclease-free N
Carrier-free Y
Endotoxin-free N
Endotoxin level Low
Endotoxin content Endotoxin LAL (EU/µg) ≤0,1
Biological activity Bioactivity Assay: TF-1 cell proliferation, ED₅₀ ≤0,25 ng/ml, Bioactivity ≥4,0×10⁶ units/mg
Purity ≥95%
Grade RUO
Formulation 0,1% Trifluoroacetic acid (TFA)
Molecular weight 15,1 kDa
Reconstitution instructions Sterile water at 0,1 mg/ml
Storage conditions –20 °C
Shipping temperature RT
Tested applications Bioassay

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