Glycyrrhetic acid ≥98%

Supplier: Cayman Chemical
Ratings: (No Reviews)

Total Ratings: 0
Avg. Ratings: 0.0 out of 5

Synonyms: 18 beta-Glycyrrhetic acid

11845-1 11845-5 11845-10
CAYM11845-1EA 80.8 GBP
CAYM11845-1 CAYM11845-5 CAYM11845-10
Glycyrrhetic acid ≥98%
Glycyrrhetic acid

18β-Glycyrrhetinic acid is an inhibitor of the complement pathway (IC50 = 35 μM). At 100 mg/kg/day, 18β-glycyrrhetinic acid is protective against diabetes complications by reducing lipid peroxidation and increasing antioxidant activity in diabetic rats. It inhibits mammalian DNA polymerases α, γ, κ and λ with IC50 values of 16,1, 19,3, 15,8 and 13,7 μM, respectively. At 100-200 μM, 18β-glycyrrhetinic acid suppresses LPS-induced TNF-α production and NF-κB activation in mouse macrophages.


18β-Glycyrrhetinic acid is a major metabolite of glycyrrhizin, one of the main constituents of licorice. Both 18β-glycyrrhetinic acid and glycyrrhizin have been shown to exhibit anti-ulcerative, anti-inflammatory and immunomodulatory properties.

Formula: C₃₀H₄₆O₄
MW: 470.69 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00003706
CAS Number: 471-53-4

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