Aggresome detection kit, PROTEOSTAT®

Supplier: Enzo Life Sciences
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PROTEOSTAT®
ENZOENZ51035K100EA 451 GBP
ENZOENZ51035K100 ALEXENZ-51035-0025 ALEXENZ-51035-K100 ENZOENZ510350025
Aggresome detection kit, PROTEOSTAT®
Assays Cellular Assays
PROTEOSTAT® Aggresome Detection Kit is a robust, quantitative detection of aggresomes relevant to the study of neurodegenerative disease, liver disease and toxicology.

  • Fixed-cell assay is optimised for antibody co-localisation studies
  • Easily quantifies aggresome and related inclusion bodies by flow cytometry
  • Useful for the study of neurodegenerative diseases, liver disease, toxicology studies and much more
  • Reliable and simple assay doesn’t require non-physiological protein mutations or genetically engineered cell lines
  • Validated under a wide range of conditions and with small molecule modulators demonstrating suitability for screening compounds of potential therapeutic value

The PROTEOSTAT® Aggresome Detection Kit is potentially applicable to the identification of small molecules that inhibit aggresome formation as well as immuno-localisation studies between aggregated protein cargo and the various proteins implicated in aggresome formation, such as histone deacetylase 6, parkin, ataxin-3, dynein motor complex and ubiquilin-1.

Delivery information: Kit contains PROTEOSTAT® Aggresome Detection Reagent, Hoechst 33342 nuclear stain, Proteasome inhibitor (MG-132) and 10X assay buffer.
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