Anti-TOP1MT Mouse Monoclonal Antibody (CF647) [clone: TOP1MT/488]

Supplier: Biotium
Ratings: (No Reviews)

Total Ratings: 0
Avg. Ratings: 0.0 out of 5


BNC470488-500EA 505 GBP
BNC470488-500 BNC470488-100
Anti-TOP1MT Mouse Monoclonal Antibody (CF647) [clone: TOP1MT/488]
Antibodies
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Type: Primary
Antigen: TOP1MT
Clonality: Monoclonal
Clone: TOP1MT/488
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG2b kappa
Reactivity: Human
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR