Pegylation reagents, Methyl-PEG-NHS-Maleimide, Pierce™

Supplier: Thermo Fisher Scientific
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Pegylation reagents, Methyl-PEG-NHS-Maleimide, Pierce™
Protein Purification Protein Purification Reagents

Pierce™ MM(PEG)n reagents are methyl-terminated PEG compounds activated with a maleimide group for covalent pegylation of sulfhydryls on proteins or assay surfaces.


  • Choice of 12 and 24 ethylene glycol units, enabling modification procedures to be optimised for a specific application
  • PEG spacer provides advantages that include increased stability, reduced tendency toward aggregation and reduced immunogenicity
  • Maleimide activated for efficient PEGylation of primary amines at pH 6,5 to 7,5; reaction of maleimide group results in formation of stable, irreversible amide bonds
  • Easy to follow instructions increase the likelihood of a successful outcome

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