Desmosine 99%, yellow solid
Supplier: MP BiomedicalsTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
Desmosine is prepared according to the method of Starcher et al. from hydrolysed neck ligament by solvent extraction and chromatography on Dowex 50.
NOTE: Extremely hygroscopic and must be stored over a desiccant such as silica gel.
Desmosine is a tetrafunctional, pyridinium ring-containing amino acids involved in elastin cross-linking. A desmosine cross-link is formed from three allysyl side chains plus one unaltered lysyl side chain from the same or neighbouring polypeptides.
Desmosine is responsible for the cross-linking of elastin leading to the formation of insoluble fibers. Urinary excretion of desmosine is a useful indicator of elastin breakdown resulting from increased elastase activity. It also acts as a biomarker of elastin degradation in chronic obstructive.
Caution: Research Use Only (RUO). Extremely hygroscopic and must be stored over a desiccant such as silica gel.
Formula:
C₂₄H₃₉N₅O₈ Storage Temperature: Refrigerator |
CAS Number:
11003-57-9 |
Specification Test Results
Identity Test | Passes |
Source | Bovine Neck Ligament |
Purity | 99% |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...