Desmosine 99%, yellow solid

Supplier: MP Biomedicals
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0219137805 0219137801
ICNA0219137805EA 627 GBP
ICNA0219137805 ICNA0219137801
Desmosine 99%, yellow solid
Desmosine

Desmosine is prepared according to the method of Starcher et al. from hydrolysed neck ligament by solvent extraction and chromatography on Dowex 50.


NOTE: Extremely hygroscopic and must be stored over a desiccant such as silica gel.


Desmosine is a tetrafunctional, pyridinium ring-containing amino acids involved in elastin cross-linking. A desmosine cross-link is formed from three allysyl side chains plus one unaltered lysyl side chain from the same or neighbouring polypeptides.


Desmosine is responsible for the cross-linking of elastin leading to the formation of insoluble fibers. Urinary excretion of desmosine is a useful indicator of elastin breakdown resulting from increased elastase activity. It also acts as a biomarker of elastin degradation in chronic obstructive.


Caution: Research Use Only (RUO). Extremely hygroscopic and must be stored over a desiccant such as silica gel.

Formula: C₂₄H₃₉N₅O₈
Storage Temperature: Refrigerator
CAS Number: 11003-57-9

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Specification Test Results

Identity Test Passes
Source Bovine Neck Ligament
Purity 99%

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