You Searched For: D-erythro-Sphingosine


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Catalog Number: (ENZOALX306011M025)
Supplier: ENZO LIFE SCIENCES
Description: PKC inhibitor
UOM: 1 * 25 mg

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Catalog Number: (ENZOBMLEI1550100)
Supplier: ENZO LIFE SCIENCES
Description: Common component of cell membranes, often as phosphatidyl conjugates. Is a potent (IC50=1-3 µM) and selective inhibitor of protein kinase C. Inhibition is competitive with diacylglycerol, phorbol dibutyrate and Ca2+ and it also inhibits PKC activation by other lipids. It acts on an equimolar basis with 1,2-dioleoylglycerol and does not affect other kinases such as MLCK and PKA. It is active in intact cells and has been identified as an endogenous constituent in HL-60 cells, neutrophils, rat liver, and brain and mouse tissues. Other activities include inhibition of phosphatidate phosphohydrolase, Na+,K+-ATPase, CTP:phosphocholine cytidylyltransferase, calmodulin-dependent enzymes, binding of factor VII to tissue factor, binding of thyrotropin releasing hormone to its receptor and activation of EGF receptor kinase, phospholipase D and casein kinase II.
UOM: 1 * 100 mg

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Supplier: Thermo Scientific
Description: Appearance: White to cream Powder or waxy solid

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Catalog Number: (J63584.MB)
Supplier: Thermo Scientific
Description: D-erythro-Sphingosine is used to inhibit protein kinase C and calmodulin-dependent enzymes, induces apoptosis. And also used to constituent of cell membranes.
UOM: 1 * 25 mg

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
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The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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