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Image Unavailable-BOSSBS-7652R-A680

Anti-DNase 2 alpha Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-7652R-A680)
Supplier: Bioss
Description: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
UOM: 1 * 100 µl
Product Image-BOSSBS-7652R

Anti-DNASE2 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-7652R)
Supplier: Bioss
Description: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7652R-CY3

Anti-DNASE2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-7652R-CY3)
Supplier: Bioss
Description: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7652R-FITC

Anti-DNASE2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-7652R-FITC)
Supplier: Bioss
Description: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7652R-A750

Anti-DNase 2 alpha Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-7652R-A750)
Supplier: Bioss
Description: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
UOM: 1 * 100 µl
Product Image-41008-T

Nucleic acid stains, PAGE GelRed™

Supplier: Biotium
Description: Stains specifically designed for DNA in polyacrylamide gels.

Environmentally Preferable

Image Unavailable-40073.

Succinimidyl ester thiazole orange DNA/RNA binding dye

Catalog Number: (40073.)
Supplier: Biotium
Description: The amine reactive succinimidyl ester of TO (thiazole orange) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups. The conjugates are expected to be essentially nonfluorescent until they are able to complex with nucleic acids, resulting in green fluorescence.
UOM: 1 * 5 mg
Image Unavailable-40028.

CF® Dye dCTP conjugates

Supplier: Biotium
Description: CF® dye-dCTP can be used to synthesise probes for in situ hybridisation, microarray, or to synthesise labelled DNA probes for in situ hybridisation and nucleic acid blotting applications.

Product Image-531-0163

Rotors and accessories for CentriVap® concentrators

Supplier: LABCONCO
Description: Rotor for evaporator, Centrifugal, Acid-resistant DNA rotor, for 72×0,5 ml or 60×1,5 - 2 ml microcentrifuge tubes, PTFE-coated aluminium

Product Image-0198-50G

Dextran sulphate sodium salt, M.W. ~ 500,000 ≥98%, Ultra Pure Grade

Supplier: VWR Chemicals
Description: Used for the detection of DNA or RNA in nucleic acid hybridisation procedures. It effectively “excludes” probe from solution, accelerating the rate of annealing.

SDS

Product Image-PALLODNABC33

Centrifugal devices for RNA and DNA extraction, NAB Nanosep®

Supplier: Cytiva (Formerly Pall Lab)
Description: The Pall Nanosep device for nucleic acid binding (NAB) incorporates a dual layer silica-based quartz glass fiber media to allow for efficient binding of DNA and RNA, while providing smooth flow and rapid processing of samples.

Image Unavailable-BOSSBS-12867R-A750

Anti-Bile Acid Receptor NR1H4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-12867R-A750)
Supplier: Bioss
Description: The steroid receptor superfamily acts through direct association with DNA sequences known as hormone response elements (HREs) and binds DNA as either homo- or heterodimers. The promiscuous mediator of heterodimerization, RXR, is the receptor for 9-cis retinoic acid, and dimerizes with VDR, TR, PPAR, and several novel receptors including LXR (also referred to as RLD-1) and FXR. FXR and LXR fall into a category of proteins termed orphan receptors? because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid.
UOM: 1 * 100 µl
Image Unavailable-CAYM11845-5

Glycyrrhetic acid ≥98%

Supplier: Cayman Chemical
Description: 18β-Glycyrrhetinic acid is an inhibitor of the complement pathway (IC<sub>50</sub> = 35 μM). At 100 mg/kg/day, 18β-glycyrrhetinic acid is protective against diabetes complications by reducing lipid peroxidation and increasing antioxidant activity in diabetic rats. It inhibits mammalian DNA polymerases α, γ, κ and λ with IC<sub>50</sub> values of 16,1, 19,3, 15,8 and 13,7 μM, respectively. At 100-200 μM, 18β-glycyrrhetinic acid suppresses LPS-induced TNF-α production and NF-κB activation in mouse macrophages.

Certificates

Image Unavailable-CAYM18425-10

Vitamin B12 (cyanocobalamin) ≥95%, crystalline solid

Supplier: Cayman Chemical
Description: Vitamin B12 is a water-soluble vitamin with roles in brain and nervous system functioning and blood formation through regulation of DNA synthesis, cellular metabolism, fatty acid metabolism, and amino acid metabolism.

SDS

Image Unavailable-BNC880488-100

Anti-TOP1MT Mouse Monoclonal Antibody (CF488A) [clone: TOP1MT/488]

Supplier: Biotium
Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Image Unavailable-BTIUBNUM0488-50

Anti-TOP1MT Mouse Monoclonal Antibody (Purified, BSA-free) [clone: TOP1MT/488]

Catalog Number: (BTIUBNUM0488-50)
Supplier: Biotium
Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.
UOM: 1 * 50 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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