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You Searched For: 15-Deoxy-delta-12,14-prostaglandin J2


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15-Deoxy-δ-12,14-prostaglandin J2 ≥97% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Prostaglandin D2 derived nuclear peroxisome proliferator-activated receptor γ (PPARγ) ligand. Induces apoptosis in a number of cell types including human lung cancer cells, synoviocytes and macrophages. Promotes differentiation of fibroblasts to adipocytes. Antiinflammatory activity. Inhibits angiogenesis. Prevents TNFα induced leptin increase in mice. TRPA1 agonist. Serious doubts as to the biological relevance of this prostaglandin have been raised. Endogenous levels seem to be too low to have any effect as a PPARγ ligand.

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