Ingenol-3,20-dibenzoate ≥97%

Supplier: ENZO LIFE SCIENCES
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BMLPE1860001
ENZOBMLPE1860001EA 253 GBP
ENZOBMLPE1860001
Ingenol-3,20-dibenzoate ≥97%
Ingenol-3,20-dibenzoate

Ingenol is a diterpenoid related to phorbol. Activates protein kinase C (PKC) and competes with [3H]phorbol dibutyrate for binding to PKCα (Ki for binding=240 nM). Induces apoptosis. Anticancer agent. Shows potent antileukemic activity in the P388 mouse assay.


Displays unusually high mouse ear inflammatory activity, even though the 20-hydroxy group is blocked with a benzoate ester. It appears likely that this high potency is due to metabolic cleavage of the 20-benzoate group, which releases the more potent ingenol 3-benzoate.


Soluble in DMSO (20 mg/ml) or ethanol (20 mg/ml).

Formula: C₃₄H₃₆O₇
MW: 556.7 g/mol
Storage Temperature: Freezer
CAS Number: 59086-90-7
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Specification Test Results

Purity ≥97%

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