Anti-RANKL Mouse Monoclonal Antibody

Supplier: ENZO LIFE SCIENCES
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ALX804244C100
ENZOALX804244C100EA 535 GBP
ENZOALX804244C100
Anti-RANKL Mouse Monoclonal Antibody
Antibodies
RANKL (TRANCE, OPGL, ODF) is a member of the TNF family. RANKL (receptor activator of NF-κB ligand) or TRANCE (TNF-related activation-induced cytokine receptor) has been implicated in interactions between T cells and dendritic cells. RANKL binds to RANK on dendritic cells, upregulates the expression of anti-apoptotic protein BcL-XL suggesting a role in dendritic cell survival. RANKL is also important in T- and B-cell maturation. As OPGL (osteoprotegerin ligand) or ODF (osteoclast differentiation factor), the same protein can both activate mature osteoclasts and mediate osteoclastogenesis.More Product Information
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