Anti-BCR Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Supplier: Bioss
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BS-6258R-A350
BOSSBS-6258R-A350EA 1270 GBP
BOSSBS-6258R-A350
Anti-BCR Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Antibodies
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21More Product Information
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