Anti-VAV3 Rabbit Polyclonal Antibody (Cy7®)

Supplier: Bioss
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BS-4286R-CY7
BOSSBS-4286R-CY7EA 844 GBP
BOSSBS-4286R-CY7
Anti-VAV3 Rabbit Polyclonal Antibody (Cy7®)
Antibodies
Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast properMore Product Information
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