Anti-IRGM Rabbit Polyclonal Antibody (Cy5®)

Supplier: Bioss
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BS-4015R-CY5
BOSSBS-4015R-CY5EA 844 GBP
BOSSBS-4015R-CY5
Anti-IRGM Rabbit Polyclonal Antibody (Cy5®)
Antibodies
IRGM belongs to a family of interferon-gamma inducible GTPases, belonging to the GTPase superfamily, and are selectively induced by IFN-gamma or bacterial lipopolysaccharide (LPS) stimulation. IRGM is primarily expressed in all cells derived from B-cell lineages, and is highly expressed in macrophages following IFN-gamma stimulation. IRGM has been shown to be required for host defences against a broad range of intracellular pathogens. Specifically, IRGM deficient mice show defects with intracellular microbial killing, phagosome maturation and autophagy. More recently IRGM has been shown toMore Product Information
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