Anti-GRAF1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Supplier: Bioss
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BS-11248R-A750
BOSSBS-11248R-A750EA 835 GBP
BOSSBS-11248R-A750
Anti-GRAF1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antibodies
Cellular Signalling by G-proteins is down-regulated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydrolysis. The GTPase regulator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare genetic subgroup of acute myeloid leukaemia (AML) cases.

Type: Primary
Antigen: GRAF1
Clonality:More Product Information
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SPECIFICATIONS

Antigen name GRAF1
Environmentally Preferable
Antigen synonyms GRAF|GTPase regulator associated with focal adhesion kinase pp125FAK|arhgap 26|GTPase regulator associated with focal adhesion kinase|Rho-type GTPase-activating protein 26|RHG26_HUMAN|OPHN1L1|Rho GTPase activating protein 26|OPHN1L|GRAF1|Rho GTPase-activating protein 26|Rho GTPase activating protein26|ARHGAP26|KIAA0621|FLJ42530|oligophrenin 1 like protein|oligophrenin1like protein|Oligophrenin-1-like protein
Antibody type Primary
Clonality Polyclonal
Conjugation Alexa Fluor® 750
Reactivity Human,Rat,Mouse
Host Rabbit
Isotype IgG
Western blot Yes
ImmunoChemistry Yes
ImmunoFluorescence Yes
Modification Unmodified
Epitope 1-100/814
Immunogen KLH conjugated synthetic peptide derived from human GRAF1
Form Liquid
Molecular weight 92 kDa
Purification Purified by Protein A
Concentration 1 µg/µl
Storage buffer Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
Storage temperature Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Shipping temperature 4 °C
Tested applications ICC

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