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Catalog Number: (USBIJ0902-06J)
Supplier: US Biological
Description: Anti-JAK3 Rabbit Monoclonal Antibody [clone: 10g85]
UOM: 1 * 100 µl


Catalog Number: (USBI037180-HRP)
Supplier: US Biological
Description: Anti-JAK3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
UOM: 1 * 200 µl


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Catalog Number: (USBIJ0902-06)
Supplier: US Biological
Description: Anti-JAK3 Rabbit Polyclonal Antibody
UOM: 1 * 250 µG


Catalog Number: (AVIVARP54305_P050)
Supplier: Aviva Systems Biology
Description: Anti-JAK3 Rabbit Polyclonal Antibody
UOM: 1 * 50 µG


Catalog Number: (ABGEAP14261A)
Supplier: Abgent
Description: Anti-JAK3 Rabbit Polyclonal Antibody
UOM: 1 * 400 µl


Catalog Number: (AVIVARP54306_P050)
Supplier: Aviva Systems Biology
Description: Anti-JAK3 Rabbit Polyclonal Antibody
UOM: 1 * 50 µG


Catalog Number: (USBI037180-BIOTIN)
Supplier: US Biological
Description: Anti-JAK3 Rabbit Polyclonal Antibody (Biotin)
UOM: 1 * 200 µl


Catalog Number: (BOSSBS-2808R-A350)
Supplier: Bioss
Description: Non-receptor tyrosine kinase involved in various processes such as cell growth, development, or differentiation. Mediates essential signaling events in both innate and adaptive immunity and plays a crucial role in hematopoiesis during T-cells development. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors sharing the common subunit gamma such as IL2R, IL4R, IL7R, IL9R, IL15R and IL21R. Following ligand binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins. Subsequently, phosphorylates the STATs proteins once they are recruited to the receptor. Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, upon IL2R activation by IL2, JAK1 and JAK3 molecules bind to IL2R beta (IL2RB) and gamma chain (IL2RG) subunits inducing the tyrosine phosphorylation of both receptor subunits on their cytoplasmic domain. Then, STAT5A AND STAT5B are recruited, phosphorylated and activated by JAK1 and JAK3. Once activated, dimerized STAT5 translocates to the nucleus and promotes the transcription of specific target genes in a cytokine-specific fashion.
UOM: 1 * 100 µl


Catalog Number: (USBI030355)
Supplier: US Biological
Description: Anti-JAK3 Mouse Monoclonal Antibody [clone: 13B433]
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-2808R-CY3)
Supplier: Bioss
Description: Non-receptor tyrosine kinase involved in various processes such as cell growth, development, or differentiation. Mediates essential signaling events in both innate and adaptive immunity and plays a crucial role in hematopoiesis during T-cells development. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors sharing the common subunit gamma such as IL2R, IL4R, IL7R, IL9R, IL15R and IL21R. Following ligand binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins. Subsequently, phosphorylates the STATs proteins once they are recruited to the receptor. Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, upon IL2R activation by IL2, JAK1 and JAK3 molecules bind to IL2R beta (IL2RB) and gamma chain (IL2RG) subunits inducing the tyrosine phosphorylation of both receptor subunits on their cytoplasmic domain. Then, STAT5A AND STAT5B are recruited, phosphorylated and activated by JAK1 and JAK3. Once activated, dimerized STAT5 translocates to the nucleus and promotes the transcription of specific target genes in a cytokine-specific fashion.
UOM: 1 * 100 µl


Catalog Number: (USBI037180-PE)
Supplier: US Biological
Description: Anti-JAK3 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM: 1 * 200 µl


Catalog Number: (BOSSBS-2808R)
Supplier: Bioss
Description: Anti-JAK3 Rabbit Polyclonal Antibody
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-3208R)
Supplier: Bioss
Description: Anti-JAK3 Rabbit Polyclonal Antibody
UOM: 1 * 100 µl


Catalog Number: (USBI037180-AP)
Supplier: US Biological
Description: Anti-JAK3 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
UOM: 1 * 200 µl


Catalog Number: (USBI037180-FITC)
Supplier: US Biological
Description: Anti-JAK3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
UOM: 1 * 200 µl


Catalog Number: (USBI037180)
Supplier: US Biological
Description: Anti-JAK3 Rabbit Polyclonal Antibody
UOM: 1 * 200 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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