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Guanosine

Supplier: Apollo Scientific
Description: Guanosine

Product Image-0193-100G

Guanosine, Ultra Pure Grade for biochemistry

Catalog Number: (0193-100G)
Supplier: VWR Chemicals
Description: Guanosine, Ultra Pure Grade for biochemistry
UOM: 1 * 100 g

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Guanosine 5'-triphosphate disodium salt

Supplier: Apollo Scientific
Description: Guanosine 5'-triphosphate disodium salt

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Guanosine ≥98%

Supplier: Apollo Scientific
Description: Guanosine ≥98%

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Guanosine 99%

Supplier: Thermo Scientific
Description: Guanosine 99%

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Product Image-ENZOALX480056M001

Guanosine-5'-O-(3-thiotriphosphate) tetralithium salt ≥85% (by HPLC)

Supplier: ENZO LIFE SCIENCES
Description: Nonhydrolysable GTP analog.

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Guanosine ≥98%

Supplier: Thermo Scientific
Description: Guanosine ≥98%

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Guanosine-5'-monophosphate disodium salt 97%

Supplier: Thermo Scientific
Description: Guanosine-5'-monophosphate disodium salt 97%

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Guanosine 3',5'-cyclic Monophosphothioate, Rp-Isomer sodium salt ≥98% (by HPLC)

Catalog Number: (ENZOALX480072M001)
Supplier: ENZO LIFE SCIENCES
Description: Inhibitor of cGMP-dependent protein kinase (PKG) 1α (cGMP antagonist). Resistant against mammalian cyclic nucleotid-dependent phosphodiesterases. No metabolic side effects. Low membrane permeability.
UOM: 1 * 1 mg

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8-(4-Chlorophenylthio)guanosine-3',5'-cyclic monophosphate triethylammonium salt ≥99% (by HPLC)

Catalog Number: (ENZOALX480031M005)
Supplier: ENZO LIFE SCIENCES
Description: Activator of PKG and CNG channels.
UOM: 1 * 5 mg

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Product Image-ENZOALX480088M005

8-(4-Chlorophenylthio)guanosine-3',5'-cyclic monophosphate sodium salt ≥99% (by HPLC)

Supplier: ENZO LIFE SCIENCES
Description: Selective activator of cGMP-dependent protein kinase (PKG) Iα, Iβ, and type II as well as of cGMP-gated ion channels.

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8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphothioate, Rp-Isomer triethylammonium salt ≥99% (by HPLC), high purity

Supplier: ENZO LIFE SCIENCES
Description: Potent selective inhibitor of cGMP-dependent protein kinase 1α, 1β and type II. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases, no metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS.

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8-(4-Chlorophenylthio)guanosine 3',5'-cyclic Monophosphothioate, Rp-Isomer triethylammonium salt ≥98% (by HPLC)

Catalog Number: (ENZOBMLCN2060001)
Supplier: ENZO LIFE SCIENCES
Description: A cell-permeable cGMP antagonist which is resistant to hydrolysis by cyclic nucleotide phosphodiesterases (Ki=0.5 µM). No metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS
UOM: 1 * 1 mg

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Anti-PPP1R12A Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-3285R-CY7)
Supplier: Bioss
Description: Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate(GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3285R-CY3

Anti-PPP1R12A Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-3285R-CY3)
Supplier: Bioss
Description: Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate(GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3285R

Anti-PPP1R12A Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-3285R)
Supplier: Bioss
Description: Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate(GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on 0800 22 33 44
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
Additional Documentation may be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalogue Number listed above. If you need further assistance, please call VWR Customer Service on 0800 22 33 44.
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