N-Methyl-bis-trifluoroacetamide acylation reagent, for GC derivatisation

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Synonyms: 2,2,2-Trifluoro-N-methyl-N-(2,2,2-trifluoroacetyl)acetamide, MBTFA

701410.110 701410.201 701410.510
MANA701410.110EA 174 GBP
MANA701410.110 MANA701410.201 MANA701410.510
N-Methyl-bis-trifluoroacetamide acylation reagent, for GC derivatisation
N-Methylbistrifluoroacetamide

This derivitisation reagent is recommended for alcohols, primary and secondary amines as well as for thiols under mild, neutral conditions. MBTFA also forms very volatile derivatives with carbohydrates.


  • Addition of halogenated carbons enhances detectability by GC-ECD
  • Derivatives are hydrolytical stable
  • Increased sensitivity by adding molecular weight

Formula: C₅H₃F₆NO₂
MW: 223.07 g/mol
Boiling Pt: 123…124 °C (760 mm Hg)
Density: 1.55 g/cm³ (d20°/4°)"
MDL Number: MFCD00000412
CAS Number: 685-27-8
EINECS: 211-680-5
UN: 3316
ADR: 9,II

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