Cobalt(III) protoporphyrin IX chloride ≥95% (by TLC)
Supplier: ENZO LIFE SCIENCES AGTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
|
Warning
|
Heme oxygenase activator.
The ability of cobalt ions to induce heme oxygenase (HO) activity in liver cells was first reported almost 30 years ago. Cobalt protoporphyrin IX (CoPP) was later shown to be a substrate for HO, now identified as the inducible isoform HO-1 (heast shock protein 32; hsp32). CoPP has been shown to down-regulate various cytochrome P450 isoforms and various mechanisms of action have been attributed to CoPP and other metalloporphyrins.
Soluble in basic aqueous solutions at pH between 8.5 to 9.0. Once in solution pH can be adjusted to physiological pH.
Formula:
C₃₄H₃₂CoN₄O₄·Cl MW: 654.5 g/mol Storage Temperature: Freezer |
CAS Number:
102601-60-5 |
Specification Test Results
Purity (TLC) | ≥95% |
Identity | Determined by UV/VIS, NMR and MS |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...