KN-93 ≥95% (by TLC)

Supplier: ENZO LIFE SCIENCES AG
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Synonyms: N-[2-[[[3-(4-Chlorophenyl)allyl](methyl)amino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamideN-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide

ENZOBMLEI2680001EA 223 GBP
ENZOBMLEI2680001
KN-93 ≥95% (by TLC)
KN-93

CaM kinase inhibitor


KN-93 is a potent, selective and cell-permeable inhibitor of CaM kinase II (IC50=370 nM). Does not significantly inhibit PKA. Causes cell-cycle arrest in NIH 3T3 fibroblasts and HeLa cells. Inhibits glucose-induced and forskolin-stimulated insulin release from isolated pancreatic islets of Langerhans. Induces G1 cell cycle arrest and apoptosis in NIH 3T3 cells.

Formula: C₂₆H₂₉ClN₂O₄S
MW: 501.04 g/mol
MDL Number: MFCD00236424
CAS Number: 139298-40-1
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