Cytochalasin D (from Zygosporium mansoni) ≥97% (by HPLC, TLC)
Supplier: ENZO LIFE SCIENCES AGTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
Synonyms:
7(S),18(R)-Dihydroxy-16(S),18-dimethyl-10-phenyl[11]cytochalasa-6(12),13(E),19(E)-triene-1,17-dione 21(R)-acetate
Cytochalasin D is a cell-permeable fungal toxin which binds to the barbed end of actin filaments inhibiting both the association and dissociation of subunits. It causes the disruption of actin filaments and inhibition of actin polymerization. It is about 10-fold more effective than cytochalasin B and does not inhibit monosaccharide transport across cell membranes. Inactivates low conductance K+ channels. Modulates CD4 cross-linking in T-lymphocytes and increases intracellular Ca2+ levels. Exhibits antitumor activity. Induces apoptosis.
- Ultra-pure
- Inhibits actin polymerization
- K+ channel blocker
Formula:
C₃₀H₃₇NO₆ MW: 507.63 g/mol |
CAS Number:
22144-77-0 |
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