Anti-DNA Polymerase lambda Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Supplier: Bioss
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BOSSBS-13020R-A680EA 802 GBP
BOSSBS-13020R-A680
Anti-DNA Polymerase lambda Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antibodies
DNA polymerase lambda (pol lambda), also designated DNA polymerase lambda or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol lambda is a member of the DNA polymerase type-X family. Pol lambda extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol ?may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol lambda and thus influences the ability of pol ?to synthesize DNA.

Type: Primary
Antigen: DNA Polymerase lambda
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 475-575/575
Host: Rabbit
Isotype: IgG
Reactivity: Rat
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