Sulpho-GMBS (N-Maleimidobutyryloxysulphosuccinimide ester), Pierce™

Supplier: Thermo Fisher Scientific
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Total Ratings: 0
Avg. Ratings: 0.0 out of 5

Synonyms: N-γ-maleimidobutyryl-oxysulphosuccinimide esterSulpho GMBS

PIER22324EA 344 GBP
PIER22324
Sulpho-GMBS (N-Maleimidobutyryloxysulphosuccinimide ester), Pierce™
Sulpho-GMBS (N-Maleimidobutyryloxysulphosuccinimide ester)

Thermo Scientific Pierce Sulfo-GMBS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short spacer arm (7.3 angstroms).


  • Reactive groups: sulfo-NHS ester and maleimide
  • Reactive towards: amino and sulfhydryl groups
  • Non-cleavable
  • Water-soluble (compare to GMBS)
  • Has a low potential for illiciting crosslinker immune response, ensuring that the primary response to the antigen-carrier protein conjugate is not diluted by a response against a determinant on the crosslinker
  • GMBS and Sulfo-GMBS are reported to be less immunogenic than SMCC


Caution: For Research Use Only. Not for use in diagnostic procedures.

Formula: C₁₂H₁₂N₂O₉S
MW: 360.297 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00153605
CAS Number: 158018-86-1

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Specification Test Results

Product Line Pierce™
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Maleimide, Sulfo-NHS Ester
Spacer Short
Form Solid
Quantity 50 mg
Type Crosslinker
Solubility Water

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