Chrysophanol ≥97.5% (by HPLC), Sigma-Aldrich®
Supplier: MerckTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
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Warning
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Synonyms:
Chrysophanic acid, 1,8-Dihydroxy-3-methylanthraquinone, 1,8-Dihydroxy-3-methylanthracene-9,10-dione
Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells. It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro.
Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway. Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus.
Keep container tightly closed in a dry and well-ventilated place.
Formula:
C₁₅H₁₀O₄ MW: 254.24 g/mol |
MDL Number:
MFCD00001208 CAS Number: 481-74-3 |
Specification Test Results
Appearance (Color), Yellow-Orange to Orange | Conforms to Requirements |
Appearance (Form) | Powder |
Infrared spectrum | Conforms to Structure |
Wavelength | 427 - 433 nm |
Extinction Coefficient | ≥10000 |
Carbon | 69.1 - 72.6% |
Purity (HPLC) | ≥97.5% |
Solubility (Turbidity), 1% in Chloroform | Clear to Hazy |
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