Chrysophanol ≥97.5% (by HPLC), Sigma-Aldrich®

Supplier: Merck
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Synonyms: Chrysophanic acid, 1,8-Dihydroxy-3-methylanthraquinone, 1,8-Dihydroxy-3-methylanthracene-9,10-dione

229075-50MG 229075-1G
SIAL229075-50MGEA 112 GBP
SIAL229075-50MG SIAL229075-1G
Chrysophanol ≥97.5% (by HPLC), Sigma-Aldrich®
Chrysophanol

Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells. It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro.


Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway. Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus.


Keep container tightly closed in a dry and well-ventilated place.

Formula: C₁₅H₁₀O₄
MW: 254.24 g/mol
MDL Number: MFCD00001208
CAS Number: 481-74-3

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Specification Test Results

Appearance (Color), Yellow-Orange to Orange Conforms to Requirements
Appearance (Form) Powder
Infrared spectrum Conforms to Structure
Wavelength 427 - 433 nm
Extinction Coefficient ≥10000
Carbon 69.1 - 72.6%
Purity (HPLC) ≥97.5%
Solubility (Turbidity), 1% in Chloroform Clear to Hazy

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