Zinc protoporphyrin ≥95% (by TLC), Calbiochem®
Supplier: Merck Millipore CalbiochemTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
Synonyms:
Protoporphyrin IX zinc(II)
, Zinc (II) Protoporphyrin IX
, Zinc(II) 3,3'-(3,8,13,17-tetramethyl-7,12-divinylporphyrin-2,18-diyl)dipropionate
A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin.
Inhibits soluble guanylyl cyclase and produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50 = 800 nM, 4 µM, and 5 µM for nNOS, iNOS, and eNOS, respectively). Inhibits relaxation induced by acetylcholine, ANP, and VIP in isolated rat aorta. Blocks interleukin-1 and prevents induction of long-term potentiation. Also useful as an indicator of iron-deficient erythropoiesis. Does not cross the blood-brain barrier.
Caution: Protect from light.
Formula:
C₃₄H₃₂N₄O₄Zn MW: 626.034 g/mol |
MDL Number:
MFCD00011612 CAS Number: 15442-64-5 |
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