N-Methyl-bis-trifluoroacetamide

Supplier: Restek
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Synonyms: 2,2,2-Trifluoro-N-methyl-N-(2,2,2-trifluoroacetyl)acetamide, MBTFA

35617 35616
REST35617EA 0 GBP
REST35617 REST35616
N-Methyl-bis-trifluoroacetamide
N-Methylbistrifluoroacetamide

Acylation derivatization reagent.


  • Most commonly used for electron capture detection
  • React with alcohols, amines, and phenols
  • Frequently used for drugs of abuse confirmation


Acylation reagents offer the same advantage available from silylation reagents: creating less polar, more volatile derivatives. In comparison to silylating reagents, the acylating reagents can more readily target highly polar multifunctional compounds, such as carbohydrates and amino acids. In addition, acylating reagents offer the distinct advantage of introducing electron-capturing groups, thus enhancing detectability during analysis.

Formula: C₅H₃F₆NO₂
MW: 223.07 g/mol
MDL Number: MFCD00000412
CAS Number: 685-27-8
EINECS: 211-680-5
UN: 2920
ADR: 8.3,II

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