Anti-KDR Rat Monoclonal Antibody (CF647) [clone: KDR721]

Supplier: Biotium
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BNC470721-500EA 505 GBP
BNC470721-500 BNC470721-100
Anti-KDR Rat Monoclonal Antibody (CF647) [clone: KDR721]
Antibodies
CD309, also known as VEGFR2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGFR2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.

Type: Primary
Antigen: KDR
Clonality: Monoclonal
Clone: KDR721
Conjugation: CF647
Epitope:
Host: Rat
Isotype: IgG1 kappa
Reactivity: Human
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