D,L-Anatabine ≥95% in ethanol

Supplier: Cayman Chemical
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Synonyms: (R,S)-Anatabine1,2,3,6-Tetrahydro-2,3'-bipyridine

CAYM11001-10EA 156 GBP
CAYM11001-10 CAYM11001-50 CAYM11001-5 CAYM11001-100
D,L-Anatabine ≥95% in ethanol
D,L-Anatabine

(R,S)-Anatabine is a minor alkaloid produced in plants of the Solanaceae family, including tobacco.


The detection of ​(R,S)-anatabine in urine is used as an indicator of tobacco use, particularly when nicotine-containing products (gum, patches, inhalers, and medications) are also being used. ​(R,S)-Anatabine increases nicotine self-administration and locomotor activity in rats. Of note, ​(R,S)-anatabine diminishes amyloid beta (Aβ) production in vitro and in vivo. ​(R,S)-Anatabine reduces (600 µg/ml) the transcription and protein levels of β-secretase, lowering the amount of Aβ1-40 and Aβ1-42 in a dose dependent manner in SHSY-5Y cells. ​(R,S)-Anatabine also dose dependently inhibits NF-κB activation.

Formula: C₁₀H₁₂N₂
MW: 160.22 g/mol
MDL Number: MFCD00078278
CAS Number: 2743-90-0

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Specification Test Results

Purity ≥95%
Formal Name 1,2,3,6-tetrahydro-2,3'-bipyridine
Formulation A solution in Ethanol
λmax 261 nm
SMILES [C@@H]1(C2=CN=CC=C2)CC=CCN1
InChI Code 1S/C10H12N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h1-4,6,8,10,12H,5,7H2
InChI Key SOPPBXUYQGUQHE-UHFFFAOYSA-N
Storage −20 °C
Shipping Wet ice in continental US; may vary elsewhere
Stability 1 year from the QC date provided on the Certificate of Analysis, when stored properly

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