Pierce™ EndoProteinase Lys-C Protease, MS Grade

Supplier: Thermo Fisher Scientific
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Pierce™
PIER90051EA 489 GBP
PIER90051
Pierce™ EndoProteinase Lys-C Protease, MS Grade
Protein Extraction Protein Extraction Reagents
Endoproteinase Lys-C protease is a highly purified native endoproteinase validated for maximum activity and stability in proteomic applications.

  • Can be used in tandem with trypsin to decrease tryptic missed cleavages thus enhancing digestion
  • Better protein characterisation results from overlapping peptides with complementary chromatographic, ionisation and fragmentation properties thereby increasing sequence coverage
  • Effective enzyme activity under highly denaturing conditions
  • C-terminal lysine cleavage specificity of 90% for a complex protein sample
  • Stable since it is provided in a lyophilised format

Applications include improved sequence coverage of protein digests, de novo sequencing, epigenetic studies and in-gel and in-solution digestion of proteins.
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