FUNCTION: Seems to promotes the survival of visceral and proprioceptive sensory neurons. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Brain and peripheral tissues. SIMILARITY: Belongs to the NGF-beta family.
A cross reactivity of less than 1% to mouse NGF, recombinant human BDNF and 5% to NT4/5 has been shown by dot blot.
Application Information:
IHC, ELISA, WB, inhibition of biological activity. A concentration of 1-10 µg/ml is recommended for IHC, ELISA, WB and inhibition of biological activity in vitro; 2-10 µg/ml (ED50) for in vivo use. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: rh NT3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Multiple points of reactivity likely because of the polyclonal nature of the antibody
Host: Rabbit
Isotype: IgG
Reactivity: Rat, Chicken, Human